TABLE 2.
Risk of treated rejection within the first year post heart transplant
Odds ratio for treated rejection within the first year after heart transplant are presented first as an unadjusted analysis followed by analyses that (1) adjusted for propensity score or (2) matched on propensity score. For each comparison the groups are stratified by crossmatch results.
| Crossmatch Group | Number of Treated Rejection/Number of Patients | Unadjusted Odds Ratio (95% CI) | Adjusted for Propensity Score Odds Ratio (95% CI) | Matched on Propensity Score Odds Ratio (95% CI) | |
|---|---|---|---|---|---|
| T-Cell | XM Negative | 821/3571 | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| XM Positive | 150/429 | 1.80 (1.46, 2.23) | 1.53 (1.23, 1.91) | 1.60 (1.15, 2.22) | |
|
| |||||
| XM Negative | 821/3571 | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) | |
| Flow Positive/ CDC Negative | 25/82 | 1.47 (0.91, 2.37) | 1.32 (0.82, 2.15) | 1.38 (0.68, 2.83) | |
| Flow Positive/ CDC Unknown | 70/232 | 1.45 (1.08, 1.94) | 1.30 (0.97, 1.75) | 1.21 (0.76, 1.92) | |
| CDC Positive | 55/115 | 3.07 (2.11, 4.46) | 2.29 (1.56, 3.37) | 3.00 (1.52, 5.94) | |
|
| |||||
| B-cell | XM Negative | 715/3215 | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) |
| XM Positive | 76/266 | 1.40 (1.06, 1.85) | 1.12 (0.84, 1.50) | 1.26 (0.83, 1.91) | |
|
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| XM Negative | 715/3215 | 1.00 (Ref) | 1.00 (Ref) | 1.00 (Ref) | |
| Flow Positive/ CDC Negative | 12/53 | 1.02 (0.54, 1.96) | 0.63 (0.31, 1.27) | 0.94 (0.46, 1.90) | |
| Flow Positive/ CDC Unknown | 48/170 | 1.38 (0.98, 1.94) | 1.18 (0.83, 1.67) | 1.24 (0.80, 1.93) | |
| CDC Positive | 16/43 | 2.07 (1.11, 3.87) | 1.66 (0.88, 3.15) | 1.86 (0.94, 3.67) | |