Table 1.
Baseline characteristics of the participants
| Young group (n = 73) | Elderly group (n = 157) | p | |
|---|---|---|---|
| Age | |||
| Years | 48 (26–59) | 69 (60–80) | <0.0001 |
| Sex | 0.727 | ||
| Female | 39 (53.42%) | 80 (50.96%) | |
| Male | 34 (46.58%) | 77 (49.04%) | |
| BMI | 0.694 | ||
| <25 (kg/m2) | 45 (61.64%) | 101 (64.33%) | |
| ≥25 (kg/m2) | 28 (38.36%) | 56 (35.67%) | |
| Laboratory testsa | |||
| ALT (U/L) | 20.46 (9.66–83.68) | 20.99 (5.00–91.85) | 0.673 |
| AST (U/L) | 22.89 (12.23–57.31) | 23.60 (6.02–116.40) | 0.163 |
| TBIL (µmol/L) | 15.20 (6.21–66.05) | 14.37 (5.11–36.86) | 0.550 |
| TC (mmol/L) | 4.60 (1.86–6.86) | 4.90 (1.70–7.61) | 0.075 |
| TG (mmol/L) | 1.42 (0.44–11.94) | 1.54 (0.38–8.87) | 0.373 |
| GLU (mmol/L) | 5.33 (1.97–20.51) | 6.05 (3.47–25.72) | <0.0001 |
| BUN (mmol/L) | 5.27 (1.52–10.32) | 6.12 (2.41–11.82) | <0.0001 |
| CRE (mmol/L) | 65.49 (39.18–88.54) | 70.53 (42.20–115.11) | 0.001 |
| Underlying diseases | 14 (19.18%) | 107 (68.15%) | <0.0001 |
| Type 2 diabetes | 3 (4.11%) | 25 (15.92%) | 0.011 |
| Hypertension | 3 (4.11%) | 32 (20.38%) | 0.001 |
| Coronary heart disease | 2 (2.74%) | 9 (5.73%) | 0.509 |
| Cor pulmonale | 0 | 2 (1.27%) | 1.000 |
| Emphysema | 0 | 6 (3.82%) | 0.180 |
| Chronic bronchitis | 0 | 18 (11.46%) | 0.003 |
| Fatty liver disease | 5 (6.85%) | 15 (9.55%) | 0.498 |
| Hypothyroidism | 1 (1.37%) | 0 | 0.317 |
Data are median (range) or n (%). Bold p values represent significant differences
aLaboratory test indices are presented in abbreviations: ALT alanine aminotransferase, AST aspartate aminotransferase, TBIL total bilirubin, TC total cholesterol, TG triglyceride, GLU blood glucose, BUN blood urea nitrogen, CRE creatinine