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. 2024 May 13;14:10896. doi: 10.1038/s41598-024-61611-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Forest plot with hazard ratios based on multivariate Cox regression analysis about TTUP. Kaplan–Meier curves of the TTUP in (b) all patients, (c) patients who underwent locoregional and surgical therapies because of initial occurrence or consecutive recurrence, and (d) patients who underwent locoregional and surgical therapies for each number of recurrences after curative therapy. Asterisks indicate statistically significant differences of means (0.01 ≤ * P < 0.05; 0.001 ≤ ** P < 0.01; *** P < 0.001). TTUP: time to untreatable progression by TACE, vs: versus.