Table 3.
Cut‑off between area under the curve, sensitivity and specificity for obesity‑ and lipid‑related indices to detect T2D by sex.
| WC | BMI | WHtR | VAI | ABSI | BRI | LAP | CI | CVAI | TyG index | TyG-BMI | TyG-WC | TyG -WHtR | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | |||||||||||||
| Area under curve | 0.625 | 0.613 | 0.632 | 0.636 | 0.571 | 0.632 | 0.656 | 0.609 | 0.654 | 0.780 | 0.700 | 0.724 | 0.734 |
| Std. Error | 0.012 | 0.012 | 0.011 | 0.012 | 0.012 | 0.011 | 0.012 | 0.012 | 0.011 | 0.010 | 0.011 | 0.011 | 0.010 |
| 95%CI | 0.602,0.648 | 0.590,0.636 | 0.609,0.654 | 0.612,0.659 | 0.549,0.594 | 0.609,0.654 | 0.633,0.679 | 0.587,0.632 | 0.631,0.676 | 0.761,0.799 | 0.679,0.722 | 0.703,0.744 | 0.713,0.754 |
| P-value | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
| Optimal cutoffs | 84.650 | 24.238 | 0.532 | 4.881 | 0.082 | 3.971 | 33.755 | 1.278 | 106.900 | 8.838 | 206.505 | 767.931 | 4.716 |
| J-Youden | 0.202 | 0.179 | 0.219 | 0.211 | 0.130 | 0.219 | 0.240 | 0.195 | 0.231 | 0.426 | 0.296 | 0.323 | 0.331 |
| Sensitivity (%) | 64.2% | 46.5% | 56.4% | 40.1% | 67.0% | 56.4% | 49.6% | 63.1% | 58.1% | 66.8% | 61.0% | 62.2% | 61.5% |
| Specificity (%) | 56.0% | 71.4% | 65.5% | 81.0% | 46.0% | 65.5% | 74.4% | 56.4% | 65.0% | 75.8% | 68.6% | 70.1% | 71.6% |
| ( +) Likelihood ratio | 1.459 | 1.626 | 1.635 | 2.111 | 1.241 | 1.635 | 1.938 | 1.447 | 1.660 | 2.760 | 1.943 | 2.080 | 2.165 |
| ( −) Likelihood ratio | 0.639 | 0.749 | 0.666 | 0.740 | 0.717 | 0.666 | 0.677 | 0.654 | 0.645 | 0.438 | 0.569 | 0.539 | 0.538 |
| Female | |||||||||||||
| Area under curve | 0.610 | 0.585 | 0.611 | 0.659 | 0.561 | 0.611 | 0.669 | 0.589 | 0.672 | 0.782 | 0.686 | 0.721 | 0.723 |
| Std. Error | 0.010 | 0.011 | 0.010 | 0.010 | 0.010 | 0.010 | 0.010 | 0.010 | 0.010 | 0.009 | 0.010 | 0.010 | 0.010 |
| 95%CI | 0.590,0.631 | 0.564,0.606 | 0.591,0.632 | 0.639,0.679 | 0.540,0.581 | 0.591,0.632 | 0.649,0.689 | 0.569,0.609 | 0.652,0.691 | 0.764,0.799 | 0.667,0.705 | 0.702,0.740 | 0.704,0.741 |
| P-value | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
| Optimal cutoffs | 89.350 | 24.599 | 0.561 | 4.810 | 0.082 | 4.571 | 36.918 | 1.301 | 115.018 | 8.940 | 221.078 | 769.129 | 5.131 |
| J-Youden | 0.165 | 0.127 | 0.178 | 0.235 | 0.106 | 0.178 | 0.253 | 0.152 | 0.266 | 0.432 | 0.285 | 0.343 | 0.323 |
| Sensitivity (%) | 48.5% | 50.8% | 63.7% | 63.7% | 65.2% | 63.7% | 66.3% | 62.4% | 63.2% | 68.5% | 59.0% | 69.2% | 63.4% |
| Specificity (%) | 68.0% | 61.9% | 54.1% | 59.8% | 45.4% | 54.1% | 59.0% | 52.8% | 63.4% | 74.7% | 69.5% | 65.1% | 68.9% |
| ( +) Likelihood ratio | 1.516 | 1.333 | 1.388 | 1.585 | 1.194 | 1.388 | 1.617 | 1.322 | 1.727 | 2.708 | 1.934 | 1.983 | 2.039 |
| ( −) Likelihood ratio | 0.757 | 0.795 | 0.671 | 0.607 | 0.767 | 0.671 | 0.571 | 0.712 | 0.580 | 0.422 | 0.590 | 0.473 | 0.531 |
WC: waist circumference; BMI: body mass index; WHtR: waist to height ratio; VAI: visceral adiposity index; ABSI: A body shape index; BRI: body roundness index; LAP: lipid accumulation product; CVAI: Chinese visceral adiposity index; CI: conicity index; TyG index: triglyceride-glucose index; TyG-BMI: TyG related to BMI; TyG-WC: TyG related to WC; TyG-WHtR: TyG related to WHtR.