Table 2.
Variable | Descriptive statistics | p | |||||
Prodromal PD | Control | Prodromal PD | |||||
n = 62 | n = 62 | vs. Control | |||||
Mean | SD | n | Mean | SD | n | ||
Sex, M/F | 37/25 | 62 | 38/24 | 62 | p = 1.000 | ||
Age, y | 63.52 | 5.96 | 62 | 63.70 | 8.04 | 62 | p = 0.793 |
RBDSQ (/13) | 9.07 | 1.83 | 62 | 2.00 | 1.79 | 62 | p < 0.001 |
Sniffin’Stick (/16) | 10.11 | 3.19 | 53 | 14.18 | 1.06 | 62 | p < 0.001 |
BSIT-A (/12) | 6.48 | 1.94 | 61 | NA | NA | 0 | NA |
Education, y | 13.00 | 4.25 | 60 | 13.76 | 3.66 | 62 | p = 0.415 |
MDS-UPDRS I (/32) | 8.22 | 5.96 | 46 | 4.65 | 4.49 | 62 | p < 0.001** |
MDS-UPDRS II (/32) | 2.68 | 4.01 | 57 | 1.10 | 1.77 | 62 | p = 0.004** |
MDS-UPDRS III (/132) | 4.71 | 6.57 | 59 | 4.19 | 5.06 | 59 | p = 0.872 |
BDI-I (/63) | 8.69 | 6.89 | 54 | 5.34 | 5.13 | 62 | p = 0.004** |
SAS (/42) | 13.56 | 5.32 | 55 | 9.93 | 5.09 | 61 | p < 0.001** |
PDQ-39 (%) | 13.32 | 12.63 | 53 | 5.87 | 6.15 | 61 | p < 0.001** |
Both groups were defined on RBDSQ, Sniffin’Stick and BSIT-A and matched for sex and age. SD, standard deviation; M, male; F, female; n, sample size; MDS-UPDRS, Movement Disorder Society –Unified Parkinson’s Disease Rating Scale; RBDSQ, REM Sleep Behavior Disorder (RBD) Screening Questionnaire; BSIT, Brief Smell Identification Test; BDI-I, Beck Depression Inventory; SAS, Starkstein Apathy Scale; PDQ-39, Parkinson’s disease questionnaire 39-item. *Significant at the unadjusted 5% level (p≤0.05) (two-tailed); **Significant at the Bonferroni-adjusted 5% level (p≤0.05/7) (two-tailed).