Table 3.
Results of neuropsychological assessments for prodromal PD (P-PD) compared to the control group
| Variable | Descriptive statistics | Significance | |||||
| Prodromal PD | Control | Prodromal PD | |||||
| n = 62 | n = 62 | vs. Control | |||||
| Mean | SD | n | Mean | SD | n | ||
| Montreal Cognitive Assessment (MoCA) (/30) | 26.05 | 2.47 | 62 | 27.39 | 2.43 | 62 | p < 0.001** |
| Trail-Making-Test Part A (TMT-A) (s) | 45.13 | 37.52 | 61 | 44.73 | 36.94 | 62 | p = 1.000 |
| Trail-Making-Test Part B (TMT-B) (s) | 111.7 | 61.77 | 61 | 89.66 | 38.50 | 62 | p = 0.030* |
| Delta-TMT (TMT-B) –(TMT-A) | 66.52 | 49.74 | 61 | 44.94 | 23.30 | 62 | p = 0.003** |
| Digit Span Test Forwards (/16) | 8.61 | 1.73 | 62 | 8.47 | 1.66 | 62 | p = 0.668 |
| Digit Span Test Backwards (/14) | 5.90 | 1.63 | 62 | 6.16 | 1.87 | 62 | p = 0.651 |
| Corsi Block-Tapping Test Forward (/16) | 8.21 | 1.50 | 62 | 8.00 | 1.34 | 61 | p = 0.450 |
| Corsi Block-Tapping Test Backward (/14) | 7.74 | 1.59 | 62 | 7.59 | 1.94 | 61 | p = 0.628 |
| Kaplan Stroop Interference Score (s) | 64.90 | 35.97 | 59 | 52.35 | 22.99 | 62 | p = 0.146 |
| Semantic Fluency Test (N Letter F, 1 min) | 10.37 | 4.43 | 60 | 11.45 | 4.50 | 62 | p = 0.307 |
| Phonemic Fluency Test (N Animals, 1 min) | 29.07 | 9.62 | 61 | 30.41 | 7.10 | 61 | p = 0.258 |
| Isaacs Set Test (N) | 32.47 | 7.58 | 58 | 34.98 | 6.09 | 58 | p = 0.058 |
| Interlocking Pentagons Test (incorrect/correct) | 2/60 | 62 | 4/58 | 62 | p = 0.676 | ||
| Cube Copying Task (incorrect/correct) | 24/38 | 62 | 9/53 | 62 | p = 0.004* | ||
| Benton’s Judgment of Line Orientation Test (/30) | 24.11 | 4.88 | 61 | 24.45 | 4.35 | 62 | p = 0.877 |
| Frontal Assessment Battery (FAB) (/18) | 15.48 | 2.17 | 52 | 16.21 | 1.53 | 62 | p = 0.091 |
| CERAD Word list (Learning) (/30) | 22.60 | 3.93 | 62 | 23.05 | 3.29 | 62 | p = 0.722 |
| CERAD Word list (Delayed Recall) (/10) | 7.10 | 2.28 | 60 | 7.59 | 1.77 | 61 | p = 0.327 |
SD, standard deviation; CERAD, Consortium to Establish Registry for Alzheimer Disease. *Significant at the unadjusted 5% level (p≤0.05) (two-tailed); **Significant at the Bonferroni-adjusted 5% level (p≤0.05/18) (two-tailed).