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Opposite patterns of age-correlated TSPO expression/microglial activation (PK PET BPnd) in inferior colliculi and cortex in 43 healthy subjects. A) TSPO expression in inferior colliculi decreased with increasing age (rho = –0.479, p = 0.001). This is a novel finding. B) TSPO expression in cortex increased with increasing age (rho = 0.331, p = 0.030). This is in accord with multiple prior studies [8–10].
