Figure 3. Association of the Biomarkers of Interest With Incident Cardiovascular Events.

NT-proBNP indicates N-terminal pro-B-type natriuretic peptide.

^aHazard ratio (HR) per unit increase = exponential function(log[HR per 1-SD increase]/SD).

^bFirst possible/definite coronary heart disease or ischemic stroke event; coronary revascularization; or died of coronary heart disease, ischemic stroke, or unclassifiable.

^cThe median follow-up was 11.8 years (IQR, 6.2-18.0 years) for atherosclerotic cardiovascular disease; all-cause mortality, 13.0 years (IQR, 7.9-19.2 years); heart failure, 12.8 years (IQR, 6.2-19.3 years); ischemic stroke, 11.9 years (IQR, 6.3-17.7 years); and myocardial infarction, 11.6 years (IQR, 6.2-17.8 years).

^dThese 3 biomarkers were combined into 1 model to investigate their independent effect on association.