Figure 4. Heat Maps Displaying the Changes in the C Statistic After the Addition of the Biomarker to the Base Model.

The changes in the C statistic were based on Cox regression models for all-cause mortality and based on Fine and Gray models for the other outcomes. The C statistics were computed based on the 1-year, 5-year, and 10-year probabilities of any events. Additional data appear in eTable 6 and eTables 10-13 in Supplement 1. The analyses stratified by age appear in eTable 16 in Supplement 1.