Table 15. Demographics and Clinical Characteristics for Gastric Cancer by Histology.
| Gastric | All | Adenocarcinoma | Squamous | Adenosquamous | P value |
|---|---|---|---|---|---|
| N (%) | 163,791 (100.0) | 103,143 (63.0) | 1,306 (0.8) | 479 (0.3) | |
| Age (years) (%) | |||||
| 0 - 14 | 45 (< 1) | 3 (< 1) | 0 (0.0) | 0 (0.0) | < 0.001 |
| 15 - 29 | 1,149 (0.7) | 493 (0.5) | 4 (0.3) | 2 (0.4) | |
| 30 - 49 | 16,632 (10.2) | 8,103 (7.9) | 76 (5.8) | 39 (8.1) | |
| 50 - 69 | 66,842 (40.8) | 41,002 (39.8) | 632 (48.4) | 257 (53.7) | |
| 70 - 89 | 79,123 (48.3) | 53,542 (51.9) | 594 (45.5) | 181 (37.8) | |
| Mean (SD) | 67.2 (13.4) | 68.5 (12.7) | 67.3 (11.7) | 65.6 (11.6) | < 0.001 |
| Median | 69 | 70 | 68 | 66 | |
| Sex (%) | |||||
| Male | 100,682 (61.5) | 68,577 (66.5) | 926 (70.9) | 346 (72.2) | < 0.001 |
| Female | 63,109 (38.5) | 34,566 (33.5) | 380 (29.1) | 133 (27.8) | |
| Race (%) | |||||
| White | 118,825 (72.5) | 74,681 (72.4) | 951 (72.8) | 371 (77.5) | < 0.001 |
| Black | 19,550 (11.9) | 11,583 (11.2) | 236 (18.1) | 61 (12.7) | |
| Other | 25,416 (15.5) | 16,879 (16.4) | 119 (9.1) | 47 (9.8) | |
| Detection Stage (%) | |||||
| Localized | 41,461 (25.3) | 22,366 (21.7) | 227 (17.4) | 59 (12.3) | < 0.001 |
| Regional | 45,864 (28.0) | 32,103 (31.1) | 337 (25.8) | 186 (38.8) | |
| Distant | 58,576 (35.8) | 38,774 (37.6) | 541 (41.4) | 206 (43.0) | |
| Unstaged | 17,890 (10.9) | 9,900 (9.6) | 201 (15.4) | 28 (5.8) | |
| Grade Differentiation (%) | |||||
| Well | 9,547 (5.8) | 4,779 (4.6) | 64 (4.9) | 3 (0.6) | < 0.001 |
| Moderate | 30,480 (18.6) | 25,698 (24.9) | 330 (25.3) | 63 (13.2) | |
| Poor | 75,552 (46.1) | 49,344 (47.8) | 542 (41.5) | 306 (63.9) | |
| Unknown | 48,212 (29.4) | 23,322 (22.6) | 370 (28.3) | 107 (22.3) | |
| Surgery (%) | |||||
| Yes | 81,339 (49.7) | 50,124 (48.6) | 342 (26.2) | 263 (54.9) | < 0.001 |
| No | 82,452 (50.3) | 53,019 (51.4) | 964 (73.8) | 216 (45.1) | |
| Chemotherapy (%) | |||||
| Yes | 63,961 (39.1) | 42,283 (41.0) | 575 (44.0) | 244 (50.9) | < 0.001 |
| No | 99,830 (60.9) | 60,860 (59.0) | 731 (56.0) | 235 (49.1) | |
| Radiotherapy (%) | |||||
| Yes | 31,035 (18.9) | 22,608 (21.9) | 505 (38.7) | 160 (33.4) | < 0.001 |
| No | 132,756 (81.1) | 80,535 (78.1) | 801 (61.3) | 319 (66.6) | |
| Incidence Rate (95% CI) | - | ||||
| All | 73.7 (73.3 - 74.1) | 43.6 (43.3 - 43.9) | 0.57 (0.54 - 0.61) | 0.19 (0.17 - 0.21) | |
| Male | 99.9 (99.2 - 100.7) | 65.2 (64.7 - 65.8) | 0.90 (0.83 - 0.97) | 0.29 (0.26 - 0.34) | |
| Female | 53.1 (52.6 - 53.5) | 26.4 (26.1 - 26.7) | 0.30 (0.27 - 0.34) | 0.10 (0.08 - 0.12) | |
| CSS (95% CI) | - | ||||
| 1-year | 56.8 (56.5 - 57.1) | 53.3 (52.9 - 53.7) | 38.2 (34.6 - 41.8) | 44.3 (38.2 - 50.3) | |
| 2-year | 43.1 (42.7 - 43.4) | 37.7 (37.3 - 38.1) | 24.9 (21.7 - 28.2) | 23.7 (18.6 - 29.2) | |
| 5-year | 32.5 (32.1 - 32.8) | 26.0 (25.7 - 26.4) | 18.4 (15.4 - 21.6) | 16.9 (12.5 - 22.0) | |
| 10-year | 28.5 (28.2 - 28.8) | 22.3 (21.9 - 22.7) | 17.1 (14.1 - 20.4) | 14.0 (9.7 - 19.0) | |
| Median (Months) | 16.6 | 13.7 | 7.7 | 10.3 | |
| RS (95% CI) | - | ||||
| 1-year | 53.5 (53.2 - 53.8) | 49.9 (49.5 - 50.3) | 35.3 (31.9 - 38.7) | 41.4 (35.5 - 47.2) | |
| 2-year | 39.1 (38.8 - 39.4) | 33.9 (33.5 - 34.3) | 22.8 (19.8 - 25.9) | 21.7 (16.9 - 26.8) | |
| 5-year | 26.5 (26.2 - 26.8) | 20.7 (20.3 - 21.0) | 14.6 (12.0 - 17.5) | 14.7 (10.7 - 19.4) | |
| 10-year | 19.0 (18.8 - 19.3) | 13.9 (13.6 - 14.3) | 10.9 (8.5 - 13.6) | 9.5 (6.1 - 13.9) | |
| Median (Months) | 14.0 | 12.0 | 6.8 | 9.4 |
P < 0.05 for all comparisons between adenocarcinoma, squamous cell carcinoma and adenosquamous cell carcinoma comparisons. Incidence rates were expressed per 100,000. CSS: cause-specific survival; RS: relative survival; CI: confidence interval; SD: standard deviation.