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FSC curves of cryo-EM maps (left panel) and model to map validation (right panel). a, paired helical tau filament from V337M mutant; b, straight tau filament from V337M mutant; c, triple tau filament from V337M mutant; d, paired helical tau filament from R406W mutant; e, paired helical tau filament from assembled V337M tau (297–391).
