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[Preprint]. 2024 Apr 30:2024.04.29.591661. [Version 1] doi: 10.1101/2024.04.29.591661

Extended Data Figure 1. V337M mutation in MAPT: Immunohistochemical localisation of tau inclusions in frontal cortex and hippocampus.

Extended Data Figure 1

A. (a-f) Tau pathology in grey matter. Higher magnifications of tissue areas within the insets in a-c are shown in d-f. Intraneuronal inclusions (blue arrows) and neuropil threads (red arrows) are in evidence. Antibody: AT8. Scale bars: 200 μm (a-c); 40 μm (d-f).

B. a,b, Low-power view; c,d, neurofibrillary tangles and neuropil threads in the pyramidal cell layer. Antibody: AT8. Scale bars: 1,000 μm (a,b) and 40 μm (c,d).