Figure 6. Adolescent CIE does not increase EtOH consumption during adulthood CIE in Fischer 344 rats.
(A) Experimental timeline. (B) EtOH intake declines throughout adolescent CIE. (C) Female and male rats show reduced EtOH intake during the first adulthood CIE session on PND 114 compared to the final adolescent CIE session on PND 74. (D) Female and male rats consume less total EtOH during adulthood CIE than in adolescent CIE. (E-G) Neither sex nor total adolescent EtOH intake were significant predictors of adulthood drinking measurements. Trendlines in E-G represent the line of best fit for each sex. * = p < .05; ** = p < .01; *** = p < .001. C-G: Each value represents EtOH intake in one cage of 2 rats.
