Table 1:

Model Parameters.

Symbol	Definition	Units	Value	Reference
$\zeta$	drag coefficient	pN s/nm	1.25	(11)
${\mathrm{\Delta }}_t$	time step length	s	0.002	(11)
Spectrin
$k_{s,S}$	spring constant	pN/nm	1	(11)
$d_{0,S}$	resting length	nm	180	(11)
$F^{th}$	force threshold for detachment	pN	0.05	(11)
Connecting edges
$k_{s,C}$	spring constant	pN/nm	1	fitted
$d_{0,C1}$	resting length for compression	nm	450	fitted
$d_{0,C2}$	resting length for extension	nm	270	fitted
$d_{0,C3}$	resting length for shear	nm	270	fitted
$d_{I,C4}$	resting length for semisphere	nm	75	fitted
$d_{I,C1}$	initial length for isotropic stress	nm	360.1389	fitted
$d_{I,C3}$	initial length for shear	nm	1138.4638	fitted
$d_{I,C4}$	initial length for semisphere	nm	[100,163.05]	fitted
Membrane
$k_b$	bending constant	pN nm	$820\left(400k_{B}T\right)$	(24)
${\theta }_0$	spontaneous curvature angle	°	0	fitted
$k_A$	area constant	pN nm	$0.0380\left(300k_{B}T/\left(2d_{0,S}^2\right)\right)$	based on (24)
Myosin
$k_{c,M}$	cable constant	pN/nm	0.1071	(11)
${\phi }_a$	myosin addition rate	1/s	0.01	(11)
${\phi }_r$	myosin removal rate	1/s	0.0063	(11)
$d_{\mathit{\text{min}}}$	minimum length	nm	135	(11)
$d_{\mathit{\text{max}}}$	maximum length	nm	450	(11)