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[Preprint]. 2024 May 1:2024.04.29.24306516. [Version 1] doi: 10.1101/2024.04.29.24306516

Figure 3: Brain activation for the SST task’s two STOP vs. GO contrasts across groups and timepoints.

Figure 3:

The HC group at baseline (n=25), the MCC group at baseline (n=40), and the MCC group at one-year (n=44) did not show activation differences between the two groups at baseline or between the two time points of the MCC group. Cannabis use frequency changes were not associated with brain activation at one-year. Figure 3a: Voxel-wise average brain activation, colored by effect size and opacity-scaled by z-scores with significance threshold (FDR=0.05) outlined, for the successful STOP vs. GO contrast (top row) and the unsuccessful STOP vs. GO contrast (bottom row) for the SST task. z-thresholds: HC group at baseline=2.77 (top) and 2.87 (bottom); MCC group at baseline=2.56 (top) and 2.62 (bottom), and MCC at one-year=2.62 (top) and 2.55 (bottom). Colorbar displays effect size. Figure 3b: Grayordinate-wise average brain activation z-scores above significance threshold (FDR=0.05) for the successful STOP vs. GO contrast (top row) and the unsuccessful STOP vs. GO contrast (bottom row) for the SST task. z-thresholds: HC group at baseline=2.25 (top) and 2.31 (bottom); MCC group at baseline=2.15 (top) and 2.20 (bottom), and MCC at one-year=2.22 (top) and 2.13 (bottom). Colorbar displays z-scores. HC=healthy control; MCC=medical cannabis card.