Table 3.

Bias risk of the in vivo studies.

Study/Bias	Selection Bias			Performance Bias		Detection Bias		Attrition Bias	Reporting Bias	Other Bias	Quality Score (“YES” Items)
	Sequence Generation	Baseline Characteristics	Allocation Concealment	Random Housing	Blinding	Random Outcome Assessment	Blinding	Incomplete Outcome Data	Selective Outcome Reporting	Other Sources of Bias
M.Joe Phillips, 2008 (USA, Korea)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Laura Fernández-Sánchez, 2011 (Spain)	NC	YES	NC	YES	YES	NC	YES	YES	YES	YES	7
Brian C. Oveson, 2011 (USA)	NC	YES	NC	NC	YES	NC	YES	YES	YES	YES	6
Arlene V. Drack, 2012 (USA)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Agustina Noailles, 2014 (Spain)	NC	YES	NC	YES	YES	NC	YES	YES	YES	YES	7
Laura Fernández-Sánchez, 2017 (Spain)	NC	YES	NC	YES	YES	NC	YES	YES	YES	YES	7
Xun Zhang, 2019 (Scotland)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Laura Fernández-Sánchez, 2022 (Spain)	NC	YES	NC	YES	YES	NC	YES	YES	YES	YES	7
Eric C. Lawson, 2016 (USA)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Ye Tao, 2019 (China)	NC	YES	NC	YES	YES	NC	YES	YES	YES	YES	7
Liping Yang, 2013 (China, USA)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Chunfei Wang, 2016 (China)	NC	YES	NC	YES	YES	NC	YES	YES	YES	YES	7
Jieming Fu, 2021 (USA)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Violeta Gómez-Vicente 2015 (Spain)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Yuta Kitamura, 2019 (Japan)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Se Joon Woo, 2010 (Korea)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Dimosthenis Mantopoulos, 2011 (USA)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5
Tao Zhang, 2012 (USA)	NC	YES	NC	NC	NC	NC	YES	YES	YES	YES	5