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. 2022 Apr 30;3:13. doi: 10.21037/tbcr-22-21

Table 14. Recommendations of adjuvant radiotherapy for patients after breast-conserving surgery.

Stratification Level I recommendations Level II recommendations
DCIS WBI ± tumor bed boost (2B) APBI (2A)
Invasive carcinoma (negative axillary lymph nodes) WBI (1A) ± tumor bed boost (1B) (I) APBI (2A)
(II) Whole-breast one-week hyperfractionated schedule (2A)
(III) WBI ± tumor bed boost + regional lymph node radiotherapy (2B)
Positive axillary lymph nodes, with axillary lymph node dissection WBI ± tumor bed boost + regional lymph node radiotherapy (1B) WBI ± tumor bed boost (2B)
1–2 positive sentinel lymph nodes, without axillary lymph node dissection WBI + tumor bed boost (1A) WBI + tumor bed boost + regional lymph node radiotherapy (including axilla) (2B)
≥3 positive sentinel lymph nodes, without axillary lymph node dissection WBI + tumor bed boost + regional lymph node radiotherapy (including axilla) (2B)

DCIS, ductal carcinoma in situ; WBI, whole breast irradiation; APBI, accelerated partial breast irradiation.