Table 2. Comparison of different localization techniques.

	Positive margins	Re-operation rate	Cost per device	Patient satisfaction	Type of study
Wire-guided localization	15–22.9% (4,5)	14.9–20.8% (4,5)	20 USD (6)	77.1% (4)	Literature review with pooled analysis (5), meta-nalysis of RCTs (4)
Intraoperative ultrasound	5–5.4% (4,7)	4.8–7% (4,7)	–	–	Meta-analyses of RCTs available (7), meta-analysis of RCTs (4)
Breast tissue marker	–	–	–	–	–
Radioguided occult lesion localization	17.0–17.2% (4,5)	9.8–12.6% (4,5)	–	85.6% (4)	Literature review with pooled analysis (5), meta-analysis of RCTs (4)
Radioactive seed localization	11.7–12.36% (4,5)	6.8–10.3% (4,5)	20–50 USD (6)	80% (4)	Literature review with pooled analysis (5), meta-analysis of RCTs (4)
Magseed®	13.3–20% (5,8,9)	11.25–13.44% (5,8,9)	400 USD (6)	100% (4)	Literature review with pooled analysis (5), cohort study (9), systematic review and pooled analysis (8)
Savi Scout®	5.6–10.6% (5)	5.3–8.6% (5)	450 USD (6)	–	Literature review with pooled analysis (5)
LOCalizer™	–	13.9% (10)	550 USD (6)	–	Systematic review (10)

RCT, randomized controlled trial.