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. 2024 Mar 12;115(5):1665–1679. doi: 10.1111/cas.16143

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© 2024 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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The diagnostic value of ITIH5 at the mRNA level for cholangiocarcinoma (CCA). (A) The positive rate of ITIH5 in the various cancer types. (B) Fold change in ITIH5 expression in the various cancer types. (C) Heatmap illustrating the expression level of ITIH5 and the tumor markers in TCGA‐CHOL. (D) Heatmap illustrating the expression level of ITIH5 and the tumor markers in TCGA‐LIHC. (E) ROC curve illustrating the diagnostic significance of ITIH5 and the tumor markers in CCA. (F) ROC curve illustrating the diagnostic significance of ITIH5 in distinguishing between CCA and hepatocellular carcinoma (HCC). CHOL, bile duct cancer; LIHC, liver hepatocellular carcinoma.