Table 4.

Neo-adjuvant therapy approach for patients (N=48) initially outside-Milan criteria who were successfully downstaged.

Therapy	N (%)	5-year RFS, N (%)	P	5-year OS, N (%)	P
Total	48 (100)	34 (70.8)	—	35 (72.9)	—
Trans-arterial chemoembolization (TACE)	45 (93.8)	31 (68.9)	0.251	32 (71.1)	0.276
Radiofrequency ablation (RFA)	6 (12.5)	5 (83.3)	0.481	6 (100)	0.111
Y-90	7 (14.6)	4 (57.1)	0.389	5 (71.4)	0.924

P values listed compare the relevant outcome to that same outcome across all patients successfully downstaged.

OS, overall survival; RFS, recurrence-free survival.