Table 3.
Effects of sodium reduction on the absolute change in eGFR from baseline and between diets
| Dietary Pattern | Absolute Change from Baseline | Low versus High | ||||
|---|---|---|---|---|---|---|
| Baseline eGFR ml/min per 1.73 m2 | High Sodium | Medium Sodium | Low Sodium | Difference | P-Trend | |
| Overall | 106.2 (0.7) | 1.35 (0.20–2.50) | 0.65 (−0.49 to 1.79) | −1.01 (−2.18 to 0.15) | −2.36 (−3.64 to −1.07) | <0.001 |
| Control diet | 105.6 (1.1) | 1.18 (−0.54 to 2.90) | 1.16 (−0.27 to 2.60) | 0.07 (−1.69 to 1.83) | −1.12 (−3.15 to 0.91) | 0.27 |
| DASH diet | 106.7 (1.0) | 1.45 (−0.10 to 2.99) | 0.14 (−1.62 to 1.90) | −1.97 (−3.50 to −0.43) | −3.41 (−5.03 to −1.79) | <0.001 |
| P interaction | 0.82 | 0.38 | 0.09 | |||
Estimates generated using generalized estimating equations (normal family, identity link, robust variance estimator, exchangeable working matrix). DASH, Dietary Approaches to Stop Hypertension.