Table 2.

Univariate and multivariate regression models for predicting eGFR mean rate of change per year^a

Regression Models and Variables	Estimate	SEM	P Value	Partial Correlation Coefficient
Univariate analysis
eGFR change from baseline at week 3, ml/min per 1.73 m2	−0.1117	0.0233	<0.0001
Sex (reference=female)	0.1430	0.4118	0.7285
Age, yr	0.0027	0.0295	0.9280
eGFR at baseline, ml/min per 1.73 m2	0.0181	0.0099	0.0675
SBP at baseline, mm Hg	0.0002	0.0152	0.9874
BMI at baseline, kg/m2	−0.0133	0.0416	0.7485
TKV at baseline, ml	−0.0003	0.0002	0.1276
BUN at baseline, mg/dl	−0.0436	0.0381	0.2530
Fasting uOsm at baseline, mOsm/kg	0.0030	0.0012	0.0146
Multivariate analysis
eGFR change from baseline at week 3, ml/min per 1.73 m2	−0.0976	0.0259	0.0002	−0.1513
Sex (reference=female)	0.4129	0.4756	0.3857	0.0352
Age, yr	0.0188	0.0363	0.6058	0.0210
eGFR at baseline, ml/min per 1.73 m2	−0.0164	0.0154	0.2878	−0.0431
SBP at baseline, mm Hg	−0.0076	0.0172	0.6588	−0.0179
BMI at baseline, kg/m2	−0.0079	0.0460	0.8639	−0.0070
TKV at baseline, ml	−0.0002	0.0003	0.4169	−0.0330
BUN at baseline, mg/dl	−0.1064	0.0517	0.0399	−0.0833
Fasting uOsm at baseline, mOsm/kg	0.0035	0.0014	0.0135	0.1000

BMI, body mass index; SBP, systolic BP; TKV, total kidney volume; uOsm, urine osmolality.

^aeGFR mean rate of change calculated for each subject using eGFR values measured from week 3 up to month 36.