Table 3.

Univariate and multivariate regression models for predicting rate of percent growth in total kidney volume per year^a

Regression Models and Variables	Estimate	SEM	P Value	Partial Correlation Coefficient
Univariate analysis
eGFR change from baseline to week 3, ml/min per 1.73 m2	0.0000	0.0002	0.8767
Sex (reference=female)	0.0314	0.0038	<0.0001
Age, yr	−0.0016	0.0003	<0.0001
eGFR at baseline, ml/min per 1.73 m2	−0.0001	0.0001	0.4393
SBP at baseline, mm Hg	0.0003	0.0001	0.0739
BMI at baseline, kg/m2	0.0024	0.0004	<0.0001
TKV at baseline, ml	0.0000	0.0000	<0.0001
BUN at baseline, mg/dl	0.0005	0.0004	0.1875
Fasting uOsm at baseline, mOsm/kg	−0.0000	0.0000	0.3745
Multivariate analysis
eGFR change from baseline at week 3, ml/min per 1.73 m2	−0.0002	0.0003	0.3784	−0.0366
Sex (male=1, female=2)	0.0203	0.0047	<0.0001	0.1756
Age, yr	−0.0023	0.0004	<0.0001	−0.2554
eGFR at baseline, ml/min per 1.73 m2	−0.0002	0.0002	0.1683	−0.0572
SBP at baseline, mm Hg	−0.0000	0.0002	0.9546	−0.0024
BMI at baseline, kg/m2	0.0020	0.0005	<0.0001	0.1787
TKV at baseline, ml	0.0000	0.0000	0.0003	0.1503
BUN at baseline, mg/dl	−0.0006	0.0005	0.2075	−0.0523
Fasting uOsm at baseline, mOsm/kg	−0.0000	0.0000	0.2952	−0.0435

BMI, body mass index; SBP, systolic BP; TKV, total kidney volume; uOsm, urine osmolality.

^aTotal kidney volume rate of percent growth calculated for each subject using total kidney volume values measured from baseline up to month 36.