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. Author manuscript; available in PMC: 2024 May 15.
Published in final edited form as: Environ Sci Technol. 2024 May 3;58(19):8417–8431. doi: 10.1021/acs.est.3c09342

Table 1.

Flame retardant parent chemicals and biomarkers quantifed in urine and serum.

Parent Chemical Biomarker in Urine
Organophosphate Esters (OPEs)
Triphenyl phosphate (TPP or TPhP) Diphenyl phosphate (DPhP)*
Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) Bis(1,3-dichloro-2-propyl) phosphate (BDCPP)
Tri-p-cresyl phosphate (TpCP) Di-p-cresyl phosphate (DpCP)
Tris(1-chloro-2-propyl) phosphate (TCPP or TCIPP) Bis(1-chloro-2-propyl) phosphate (BCPP)
Tributyl phosphate or Tri-n-butyl phosphate (TBP or TnBP) Dibutyl phosphate (DBP or DBuP)
Tribenzyl phosphate (TBzP) Dibenzyl phosphate (DBzP)
Tris(2-chloroethyl) phosphate (TCEP) Bis(2-chloroethyl) phosphate (BCEtP)
Tri-o-cresyl phosphate (ToCP) Di-o-cresyl phosphate (DoCP)
Non-PBDE-brominated flame retardant
2-Ethylhexyl 2,3,4,5-tetrabromobenzoate (EH-TBB) 2,3,4,5-Tetrabromobenzoic acid (TBBA)
Parent Chemical Biomarker in Serum

Polybromianted Diphenyl Ethers (PBDEs)
2,2’,4-tribromodiphenyl ether (BDE-17) BDE-17
2,4,4’-tribromodiphenyl ether (BDE-28) BDE-28
2,2’,4,4’-tetrabromodiphenyl ether (BDE-47) BDE-47
2,3’,4,4’-tetrabromodiphenyl ether (BDE-66) BDE-66
2,2’,3,4,4’-pentabromodiphenyl ether (BDE-85) BDE-85
2,2’,4,4’,5-pentabromodiphenyl ether (BDE-99) BDE-99
2,2’,4,4’,6-pentabromodiphenyl ether (BDE-100) BDE-100
2,2’,4,4’,5,5’-hexabromodiphenyl ether (BDE-153) BDE-153
2,2’,4,4’,5,6’-hexabromodiphenyl ether (BDE-154) BDE-154
2,2’,3,4,4’,5’,6-heptabromodiphenyl ether (BDE-183) BDE-183
2,2’,3,3’,4,4’,5,5’,6-nonabromodiphenyl ether (BDE-206) BDE-206
decabromodiphenyl ether (BDE-209) BDE-209
*

Other examples of parent compounds for this biomarker: Isopropylphenyl diphenyl phosphate, t-Butylphenyl diphenyl phosphate, and EH-DPhP