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. 2024 Apr 11;21(5):809–813. doi: 10.1038/s41592-024-02237-2

Extended Data Fig. 5. Processing with brainlife.io is valid, reliable, and reproducible.

Extended Data Fig. 5

Top row: Validity measures derived using the HCPTR data preprocessed and provided by the HCP Consortium compared to data preprocessed on brainlife.io. Each dot corresponds to the ratio for a given subject between data preprocessed and provided by the HCP Consortium vs data preprocessed on brainlife.io in a given measure for a given structure. Pearson’s correlation (r), root mean squared error (rmse), and a linear fit between the test and retest results were calculated and provided. v. Tract average AD, FA, MD, and RD. Dark colors represent data within ±1 standard deviation. 50% opacity represents data within 1-2 standard deviations. 25% opacity represents data outside 2 standard deviations. Bottom row: Test-retest reliability measures derived from derivatives of the HCPTR dataset generated using brainlife.io. Each dot corresponds to the ratio between a test-retest subject and a given measure for a given structure. Pearson’s correlation (r), root mean squared error (rmse), and a linear fit between the test and retest results were calculated and provided. w. Tract average AD, FA, MD, and RD. Dark colors represent data within ±1 standard deviation. 50% opacity represents data within 1-2 standard deviations. 25% opacity represents data outside 2 standard deviations. c. Computational reproducibility values derived by repeating runs of brainlife.io Apps using the HCPTR dataset and the CAN dataset. Each dot corresponds to the ratio for a given subject between repeated runs of each App for a given structure. Pearson’s correlation (r), root mean squared error (rmse), and a linear fit between the repeated runs was calculated. Destrieux Atlas Parcels volume (mm3). Tract-average fractional anisotropy (FA). Node-average functional connectivity (FC). Primary gradient values derived from resting state fMRI. Peak alpha frequency (Hz) in the alpha band derived from MEG.