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. 2024 Apr 8;144(5):2027–2038. doi: 10.1007/s00402-024-05274-w

Table 3.

The association in univariate and multivariate analysis between patients’ characteristics and DFS; only the margin obtained during index surgery and gender resulted statistically associated in multivariate analysis

Disease-free survival Univariate analysis Multivariate analysis
HR (CI95%) p value HR (CI95%) p value
Gender
 Male vs female 3.263 (1.189–8.949) 0.022 4.645 (1.505–14.335) 0.008
Age 1.010 (0.989–1.032) 0.338 ns
Previous therapy
 Yes vs no 1.086 (0.476–2.479) 0.844 ns
Histology 0.729 ns
 Condrodarcoma vs malign tumor 1.468 (0.325–6.627) 0.617
 Cordoma vs malign tumor 0.793 (0.315–1.997) 0.622
 Cordoma vs condrosarcoma 0.540 (0.111–2.634) 0.446
Patholgy results 0.001 < 0.0001
 Intralesional vs wide 13.916 (2.993–64.703) 0.001 13.614 (2.871–64.559) 0.001
 Marginal vs wide 1.956 (0.531–7.199) 0.313 1.015 (0.263–3.919) 0.98
 Marginal vs intralesional 0.141 (0.046–0.432) 0.001 0.075 (0.20–0.282) 0.001
N. levels 1.132 (0.736–1.742) 0.573 ns
Tumor volume 1.001 (0.999–1.002) 0.580 ns