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. 2024 Mar 25;25(5):2306–2322. doi: 10.1038/s44319-024-00122-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the data associated with this article, unless otherwise stated in a credit line to the data, but does not extend to the graphical or creative elements of illustrations, charts, or figures. This waiver removes legal barriers to the re-use and mining of research data. According to standard scholarly practice, it is recommended to provide appropriate citation and attribution whenever technically possible.

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(A) Average nonsynonymous pairwise nucleotide diversity per site (π_N) and average synonymous pairwise nucleotide diversity per site (π_S). (B) π_S vs π_N of the coding sequence of NLRs with per group linear regressions. The neutral expectation, π_S = π_N, is shown as a gray dotted line. (C) Mutation probability score of hv and non-hvNLRs. (D) Percentage of codons under positive selection determined by MEME (episodic), and FEL (pervasive). Data Information: For all comparisons, n = 97 for non-hvNLRs and n = 35 for hvNLRs, with n referring to the number of genes tested. The significance shown is the result of unpaired Wilcoxon rank-sum tests, with *** indicating a P value < 0.001. Source data are available online for this figure.