Skip to main content
. 2024 Mar 19;84(10):1680–1698. doi: 10.1158/0008-5472.CAN-23-2701

Figure 7.

Figure 7. ATG-101 demonstrated good safety profile. A and B, Mean serum concentrations of AST (A) and ALT (B) of cynomolgus monkeys over the study period at the indicated doses. C, Representative images of hematoxylin and eosin staining of liver tissue collected from the animals in the study. D, PD-L1 RO on CD3+ T cells over the study period at the indicated doses. AF647-labeled parental anti-PD-L1 antibody was employed to assist in the measurement of the ratio of free receptor. Median is shown in the figure (n = 10 per group, 5 female mice and 5 male mice.). E, Concentrations of IL2 and IL6 of cynomolgus monkeys in the study over the study period at the indicated doses. Means ± SEM are shown.

ATG-101 demonstrated good safety profile. A and B, Mean serum concentrations of AST (A) and ALT (B) of cynomolgus monkeys over the study period at the indicated doses. C, Representative images of hematoxylin and eosin staining of liver tissue collected from the animals in the study. D, PD-L1 RO on CD3+ T cells over the study period at the indicated doses. AF647-labeled parental anti-PD-L1 antibody was employed to assist in the measurement of the ratio of free receptor. Median is shown in the figure (n = 10 per group, 5 female mice and 5 male mice.). E, Concentrations of IL2 and IL6 of cynomolgus monkeys in the study over the study period at the indicated doses. Means ± SEM are shown.