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. 2023 Oct 27;30(10):2233–2244. doi: 10.1158/1078-0432.CCR-22-3573

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©2023 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 3. Forest plots of PFS for patients with and without specific genomic alterations at baseline in MONARCH 3 (TR population). Cell cycle–related genes consist of CCND1, CCND2, CDK4, CDK5, CDKN2A, CCNE1, RB1, and TP53. MAPK genes consist of ARAF, BRAF, HRAS, KRAS, MAPK1, MAP2K1, MAP2K2, MAP3K1, NRAS, and RAF1 (CRAF). CI, confidence interval; ITT, intent-to-treat; NA, not achieved; PFS, progression-free survival; TR, translation research. — Forest plots of PFS for patients with and without specific genomic alterations at baseline in MONARCH 3 (TR population). Cell cycle–related genes consist of CCND1, CCND2, CDK4, CDK5, CDKN2A, CCNE1, RB1, and TP53. MAPK genes consist of ARAF, BRAF, HRAS, KRAS, MAPK1, MAP2K1, MAP2K2, MAP3K1, NRAS, and RAF1 (CRAF). CI, confidence interval; ITT, intent-to-treat; NA, not achieved; PFS, progression-free survival; TR, translation research.