TABLE 3.
Changes in the network of interactions between the HIV-1 RT and dTTP for the isolate q759a
| RT structural model | Changes
|
|
|---|---|---|
| Hydrogen bonds | Nonbonded contacts | |
| Wild type | Y115, A114, D113, R72, D185, Q151, V111 | D185, Q151, Y115, A114 |
| Isolate q759 | F115, A114, D113 | D185, M151, F115, A114 |
Wild-type RT contacts were calculated based on the structure reported in reference 8. Boldface indicates mutations compared to the wild type.