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Mechanisms of resistance and susceptibility of new beta-lactams. Adapted from Doi et al. [151]
| Carbapenemase | |||||||
|---|---|---|---|---|---|---|---|
| Class A | Class B | Class D | |||||
| KPC, GES | MBL: VIM, NDM, IMP | OXA-48 | PAER MR | Aanetobacter | S. maltophilia | ||
| Ceftazidime-avibactam | S | R | S | S | R | R | |
| Ceftolozane-tazobactam | R | R | R | S | R | R | |
| Imipenem-relebactam | S | R | R | S | R | R | |
| Meropenem-vaborbactam | S | R | R | R | R | R | |
| Cefiderocol | S | S | S | S | S | S | |
R: resistant, S: susceptible, PAER MR: P. aeruginosa multi-drug resistant.
