Table 2.
PXR activation by phytochemicals of T. crispa and T. sinensis.
| Plant source | Test sample | Fold induction in PXR activity at |
||
|---|---|---|---|---|
| 50 μg/mL | 25 μg/mL | 12.5 μg/mL | ||
|
| ||||
| T.sinensis | Tinosineside A | 1.53 ± 0.11 | 1.50 ± 0.00 | 1.42 ± 0.06 |
| T. sinensis | Tinosinen | 1.42 ± 0.06 | 1.67 ± 0.02 | 1.48 ± 0.06 |
| T. sinensis | Tinosposinoside | 1.52 ± 0.15 | 1.55 ± 0.08 | 1.30 ± 0.08 |
| T. sinensis | Cordifoliside C | 1.95 ± 0.04 | 1.47 ± 0.03 | 1.22 ± 0.06 |
| T. crispa | Borapetoside B | NA | NA | NA |
| T. crispa | Borapetoside C | NA | NA | NA |
| T. crispa | Borapetoside F | NA | NA | NA |
| T. crispa | (2R, 5R,6R,8R,9S, 10S, 12S) –15,16-epoxy-2-hydroxy-6-O-(β-D-glucopyranosyl) -cleroda-3,13(16),14-trien-17,12-olid-18-oic acid methyl ester | 1.39 ± 0.11 | 1.01 ± 0.13 | 0.93 ± 0.04 |
| T. crispa | Baenzigeride A | 1.96 ± 0.16 | 1.54 ± 0.16 | 1.18 ± 0.09 |
| T. crispa | Columbin | 3.58 ± 0.61 | 2.89 ± 0.62 | 2.02 ± 0.02 |
| T .crispa | Cycloeucalenol | 2.42 ± 0.30 | 1.91 ± 0.23 | 1.42 ± 0.06 |
| T. crispa | N trans-feruloyl tyramine | 2.29 ± 0.41 | 2.16 ± 0.27 | 1.59 ± 0.07 |
| T. crispa | Palmatine | 1.43 ± 0.00 | 1.30 ± 0.00 | 1.08 ± 0.00 |
| Jatrorrhizine | 2.44 ± 0.05 | 1.94 ± 0.04 | 1.48 ± 0.01 | |
| Magnoflorine | 1.41 ± 0.12 | 1.16 ± 0.15 | 1.01 ± 0.15 | |
| Berberine | NA | NA | NA | |
NA-No activation.