Influence of miRNA-140-5p on inflammatory factors, Hyp and TDSCs proliferation. NC – The TDSCs were treated with normal treatment; Model – The TDSCs were treated with 50 ng/ml TGF-β1; Vector – The cells were transfected with empty vector based on the model; miRNA-NC – The cells were transfected with miRNA-NC (negative control) based on the model; miRNA – The cells were transfected with miRNA-140-5p based on the model; si-TLR4 – The cells were transfected with si-TLR4 (knockdown TLR4) based on the model; si-TLR4 + miRNA – The cells were transfected with miRNA-140-5p and si-TLR4 (knockdown TLR4) based on the model; miRNA + TLR4 – The cells were transfected with miRNA-140-5p and TLR4 (TLR4 overexpression) based on the model. A – miRNA-140-5p affect inflammatory factors by ELISA assay. ***P < 0.001, compared with NC group; ##p < 0.01, compared with miRNA-NC group; $$p < 0.01, compared with miRNA group; ΔΔp < 0.01, compared with si-TLR4 + miRNA group. B – miRNA-140-5p affect Hyp concentration by ELISA assay. ***P < 0.001, compared with NC group; ##p < 0.01, compared with miRNA-NC group; $$p < 0.01, compared with miRNA group; ΔΔp < 0.01, compared with si-TLR4 + miRNA group. C – miRNA-140-5p affects cell proliferation by MTT assay. ***P < 0.001, compared with NC group; ##p < 0.01, compared with miRNA-NC group; $$p < 0.01, compared with miRNA group; ΔΔp < 0.01, compared with si-TLR4 + miRNA group