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. 2024 Mar 19;20(5):3228–3250. doi: 10.1002/alz.13788

TABLE 1.

Demographics (full sample and subsamples).

Full sample CN (N = 147) AD (= 141) bvFTD (N = 44)
χ2 test
Sex (M/F) 53/94 66/75 35/9 AD vs. CN bvFTD vs. CN
χ2 = 7.07, = 0.008 χ2 = 17.01, P < 0.0001
Student t test
Age (years) 67 ± 8.3 74 ± 6.2 69.5 ± 8.0 AD vs. CN bvFTD vs. CN
= 7.56, < 0.0001 = 1.87, = 0.0630
Student t test
Education (years) 13.2 ± 4.5 10.2 ± 4.9 13.1 ± 5.3 AD vs. CN bvFTD vs. CN
= −5.66, P < 0.001 t = −0.73, P = 0.4688
Sample 1 CN (N = 45) AD (N = 31) bvFTD (N = 18)    
χ2 test
Sex (M/F) 17/29 14/17 13/5 AD vs. CN bvFTD vs. CN
χ2 = 0, P = 1 χ2 = 10.74, P = 0.001
Student t test
Age (years) 71 ± 7.2 76 ± 7.5 68 ± 9.9 AD vs. CN bvFTD vs. CN
t = 2.70, P = 0.008 t = −1.25, P = 0.22
Student t test
Education (years) 14.7 ± 4 9.9 ± 4.9 15.4 ± 4.8 AD vs. CN bvFTD vs. CN
t = −4.63, P < 0.001 t = 0.57, P = 0.57
Sample 2 CN (N = 101) AD (N = 110) bvFTD (N = 26)    
χ2 test
Sex (M/F) 36/65 53/58 26/10 AD vs. CN bvFTD vs. CN
χ2 = 7.09, P = 0.008 χ2 = 7.09, P < 0.0048
Student t test
Age (years) 65.6 ± 8.2 73.3 ± 5.7 70.4 ± 6.3 AD vs. CN bvFTD vs. CN
t = 8.09, P < 0.0001 t = 2.98, P = 0.0034
Student t test
Education (years) 12.6 ± 4.5 10.3 ± 4.9 11.7 ± 5.0 AD vs. CN bvFTD vs. CN
= −3.74, P = 0.0002 t = −1.34, P = 0.1826

Notes: Values constituted by proportion (sex) and mean ± standard deviation (age and education). Categorical variables were analyzed with Pearson chi‐squared (χ2) test. Continuous variables were analyzed through Student t tests.

Abbreviations: AD, Alzheimer's disease; bvFTD, behavioral variant of frontotemporal dementia; CN, healthy controls.