Table 1.
Univariate and Multivariate-Adjusted Regression Analysis of KSHV Prevalence for Demographic, Clinical, and Social Variables
| Univariate/Unadjusted | Multivariate/Adjusted | ||||
|---|---|---|---|---|---|
| Variable | OR (95% CI) | P Value | P Value (LRT) | OR (95% CI) | P Value |
| Race: subgroups | <.001 | … | … | ||
| Hispanic | 1 [Reference] | … | … | ||
| Non-Hispanic White | 0.63 (.26–1.50) | .298 | … | … | |
| Non-Hispanic Black | 2.78 (1.52–5.08) | <.001 | … | … | |
| Non-Hispanic other | 0.30 (.06–1.41) | .127 | … | … | |
| Race: binary | <.001 | … | … | ||
| Non-Black | 1 [Reference] | 1 [Reference] | … | ||
| Black | 3.76 (2.31–6.11) | <.001 | 1.62 (.91–2.88) | .100 | |
| Age, y | .041 | … | … | ||
| 16 to 22 | 1 [Reference] | 1 [Reference] | … | ||
| 23–26 | 2.05 (1.16–3.61) | .013 | 1.91 (1.00–3.65) | .049 | |
| 27–29 | 1.49 (.84–2.64) | .169 | 1.43 (.74–2.75) | .289 | |
| Depression score | 1.00 (.96–1.04) | .871 | .871 | … | … |
| HIV status | <.001 | … | … | ||
| Negative | 1 [Reference] | 1 [Reference] | … | ||
| Positive | 6.99 (4.31–11.35) | <.001 | 4.11 (2.37–7.13) | <.001 | |
| FTA statusa | <.001 | … | … | ||
| Negative | 1 [Reference] | 1 [Reference] | … | ||
| Positive | 5.05 (3.12–8.18) | <.001 | 2.80 (1.62–4.83) | <.001 | |
| No. of sex partners (SQRT) | 0.96 (.82–1.14) | .658 | .655 | … | … |
| PrEP ever takenb | .003 | … | … | ||
| No | 1 [Reference] | … | … | ||
| Yes | 0.39 (.20–.76) | .006 | … | … | |
| Cannabis use: past 3 mo | .640 | … | … | ||
| Never | 1 [Reference] | … | … | ||
| Once or twice | 1.30 (.66–2.57) | .454 | … | … | |
| Monthly | 1.35 (.60–3.02) | .469 | … | … | |
| Weekly | 1.64 (.79–3.38) | .184 | … | … | |
| Daily | 1.37 (.80–2.37) | .254 | … | … | |
| Any cannabis use: past 3 mo | .136 | … | … | ||
| Never | 1 [Reference] | … | … | ||
| At least once | 1.40 (.90–2.18) | .138 | … | … | |
| Any methamphetamine use: past 3 moc | .038 | … | … | ||
| Never | 1 [Reference] | … | … | ||
| At least once | 3.47 (1.02–11.75) | .046 | … | … | |
| Noncannabis substance use: past 3 mod | .169 | … | … | ||
| No | 1 [Reference] | … | … | ||
| Yes | 0.73 (.47–1.14) | .169 | … | … | |
| No. of noncannabis substances used: past 3 mod | 0.96 (.86–1.08) | .505 | .503 | … | … |
Abbreviations: FTA, fluorescent treponemal antibody; KSHV, Kaposi sarcoma–associated herpesvirus; LRT, likelihood ratio test; OR, odds ratio; PrEP, preexposure prophylaxis; SQRT, square root.
aAbsorption test to determine syphilis status.
bMedication to reduce risk of HIV acquisition.
cMethamphetamine use has a limited sample size, with only 12 individuals indicating that they used it at least once in the past 3 months.
dCocaine, methamphetamine, inhalants, sedatives, hallucinogens, opioids, pain killers, ecstasy.