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. 2023 Nov 29;229(5):1498–1508. doi: 10.1093/infdis/jiad441

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Figure 2. — BCG shedding at the challenge site is positively correlated with dose escalation. Participants (n = 83) were enrolled and received 2 × 10⁶ (black), 4 × 10⁶ (red), or 8 × 10⁶ (blue) CFUs of BCG intradermally on day 1. BCG shedding at the challenge site was assessed by (A) qPCR, (B) CFUs, or (C) MGIT TTP, and results from all swab specimen cultures are presented as geometric means over time. BCG, Bacillus Calmette-Guérin; CFU, colony-forming unit; qPCR, quantitative polymerase chain reaction; TTP, time to positivity.