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. 2024 May 15;19(5):e0302744. doi: 10.1371/journal.pone.0302744

Table 6. Characteristics of TB patients with substance use disorder.

Characteristic Yes No Bivariate Multivariate
Sub-category n (%) n (%) cOR p-value aOR 95%CI p-value
Gender Female 1 (0.7) 141 (99.3) 1 1
Male 46 (20.4) 179 (79.6) 36.2 0.00 16.5 1.9–145.2 0.01
Age (yrs) 18–34 16 (8.4) 174 (91.6)
35–49 22 (19) 94 (81) 2.55 0.00 0.79 0.27–2.32 0.66
50–64 9 (18.8) 39 (81.2) 2.51 0.04 1.14 0.29–4.45 0.85
65+ 0 (0) 13 (100) - -
Education No formal education 1 (7.7) 12 (92.3) 1 1
Primary 25 (21.4) 92 (78.6) 3.26 0.28 1.23 0.81–18.7 0.88
Secondary 15 (11.6) 114 (88.4) 1.58 0.67 0.78 0.05–12.0 0.05
Tertiary 4 (3.8) 101 (96.2) 0.48 0.52 0.22 0.01–4.41 0.33
Occupation Formal 5 (9.6) 47 (90.4) 1 1
Informal 33 (17.9) 151 (82.1) 2.05 0.16 0.81 0.24–2.78 0.74
Unemployed 7 (9.7) 65 (90.3) 1.01 0.98 0.62 0.13–2.96 0.55
Student 2 (3.4) 57 (96.6) 0.33 0.2 0.71 0.09–5.84 0.75
Marital status Married 19 (12.3) 136 (87.7) 1 1
Single 13 (8.5) 140 (91.5) 0.66 0.28 2.12 0.66–6.88 0.21
Sep /divorced 13 (30.2) 30 (69.8) 3.1 0.00 2.38 0.82–6.87 0.11
Widowed 2 (12.5) 14 (87.5) 1.02 0.98 2.17 0.27–17.5 0.47
Comorbidities Without 28 (12.7) 193 (87.3) 1 1
With 19 (13) 127 (87) 1.03 0.92 1.03 0.43–2.44 0.95
Smoking Never 11 (4) 263 (96) 1 1
Yes 36 (38.7) 57 (61.3) 15.1 0.00 3.57 1.41–9.03 0.01
Alcohol use Never 2 (1.1) 181 (98.9) 1 1
Yes 45 (24.5) 139 (75.5) 29.3 0.00 7.69 1.42–41.5 0.02
Patient type New 34 (11) 276 (89) 1 1
Previously treated 13 (22.8) 44 (77.2) 2.4 0.02 0.90 0.33–2.43 0.84
Type of TB PTB bacteriological confirmed 35 (13.9) 217 (86.1) 1 1
PTB clinically diagnosed 5 (15.6) 27 (84.4) 1.15 0.79 1.03 0.25–4.2 0.97
Extra-PTB 7 (8.4) 76 (91.6) 0.57 0.20 1.04 0.36–2.99 0.94
Treatment phase Initiation 25 (12.4) 176 (87.6) 1 1
Continuation 22 (13.2) 144 (86.8) 1.08 0.82 0.89 0.38–2.05 0.78
Family psychiatric history No 36 (11) 291 (89) 1 1
Yes 11 (27.5) 29 (72.5) 3.07 0.00 3.97 1.32–12.0 0.01

PTB–pulmonary TB; Extra-PTB–extrapulmonary TB