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. Author manuscript; available in PMC: 2024 May 15.
Published in final edited form as: Circulation. 2023 Nov 30;149(1):e1–e156. doi: 10.1161/CIR.0000000000001193

Table 14.

Situations in Which Long-Term Anticoagulation Is Contraindicated and Situations When It Remains Reasonable

Long-Term Anticoagulation Contraindicated Long-Term Anticoagulation Is Still Reasonable
Severe bleeding due to a nonreversible cause involving the gastrointestinal, pulmonary, or genitourinary systems
Spontaneous intracranial/intraspinal bleeding due to a nonreversible cause
Serious bleeding related to recurrent falls when cause of falls is not felt to be treatable
Bleeding involving the gastrointestinal, pulmonary, or genitourinary systems that is treatable
Bleeding related to isolated trauma
Bleeding related to procedural complications