Table 7.

C₂HEST Risk Score for Detecting Incident AF^*

Acronym	Risk Factor	Points
C2	CAD/COPD	1–2
H	Hypertension	1
E	Elderly (age ≥75 y)	2
S	Systolic heart failure	2
T	Thyroid disease (hyperthyroidism)	1

^*Total points 0–8. For the C₂HEST score, the C statistic was 0.749, with 95% CI of 0.729–0.769.¹⁰ The incident rate of AF increased significantly with higher C₂HEST scores.

AF indicates atrial fibrillation; CAD, coronary artery disease; C₂HEST, coronary artery disease or chronic obstructive pulmonary disease [1 point each]; hypertension [1 point]; elderly [age ≥75 y, 2 points]; systolic HF [2 points]; thyroid disease [hyperthyroidism, 1 point]; and COPD, chronic obstructive pulmonary disease.