TABLE 3.
Recommendations for Other Vaccines That May be Indicated for Adults With Cancer and Coexisting Health Conditions
| Vaccine | Type | Other Risk Factor | Recommendation |
|---|---|---|---|
| Haemophilus influenzae type b vaccination (Hib) | Nonlive | Anatomic asplenia | For elective splenectomy: one dose at least 14 days before splenectomy (preferred) |
| Functional asplenia | One dose if previously did not receive Hib | ||
| Hepatitis A vaccination | Nonlive | Chronic liver disease, HIV, MSM, homelessness, injection or noninjection drug use, occupational exposure, travel | Two-dose series HepA or three-dose series HepA-HepB |
| Meningococcal vaccinationa | Men ACWY (nonlive) | Anatomic or functional asplenia, complement component deficiency, complement inhibitor (eg, eculizumab, ravulizumab), Travel, Occupational, Military recruits, Residential living for college students | Two-dose series MenACWY-D Frequency: 8 weeks apart Revaccinate every 5 years if risk remains |
| Men B (nonlive) | Anatomic or functional asplenia (including sickle cell disease), persistent complement component deficiency, complement inhibitor (eg, eculizumab, ravulizumab) use, occupational (microbiologists), pregnancy, MSM outbreak setting | Two-dose primary series MenB-4C at least 1 month apart Or three-dose primary series MenB-FHbp at 0, 1-2, 6 months Revaccinate every 2-3 years if risk remains |
|
| IPV | Nonlive | Travel Community risk (eg, wastewater detection of vDPV) |
Single booster |
| MMR | Live | No evidence of immunity: HIV (CD4 >200 for 6 months), HCP, outbreak setting, travel | Contraindicated with cancer treatment and other immunocompromising conditions |
| Varicella | Live | Postexposure | Contraindicated with cancer treatment and other immunocompromising conditions |
| MVA (Monkeypox) | Live (replication-deficient) | Postexposure, Occupational exposure (laboratory worker), high risk |
Safe to administer in persons with HIV or those on immunosuppressive therapies |
| Monkeypox and smallpox (ACAM2000) | Live | Contraindicated with cancer treatment and other immunocompromising conditions |
NOTE. Adapted from CDC Adult Immunization Schedule By Medical Condition and Other Indication (https://www.cdc.gov/vaccines/schedules/hcp/imz/adult-conditions.html).15
Abbreviations: HCP, health care personnel; Hib, Haemophilus influenzae type b; IPV, inactivated poliovirus vaccine; Men, meningococcal; MMR, measles, mumps, and rubella; MSM, men who have sex with men; MVA, modified Vaccina Ankara; vDPV, vaccine-derived poliovirus.
a
Patients eligible for both meningococcal vaccines can receive the new Men ABCWY.