Primary and metastatic STLMS risk stratification.
A, Disease-specific survival (DSS) for patients from the MSK cohort stratified by FNCLCC grade (A) represented by Kaplan-Meier curves. Alluvial diagram comparing age (≤ 60 years old, > 60 years old), sex, primary site, histologic grade (FNCLCC, mitotic count, necrosis) (versus genomic risk groups in STLMS. B, A 3-tier genomic stratification scheme is proposed for DSS from the MSK cohort of 151 STLMS patients that were primary at presentation. C, DSS for 44 patients with metastatic STLMS from the MSK cohort stratified by RB1 mutation status is represented by Kaplan-Meier curve.