Table 1.
Demographic and clinical data of the depressed patients and healthy controls (HC) included in the present study.
| Variables | HC (n = 20) | MDD (n = 30) | F/W/X2 | df | p |
|---|---|---|---|---|---|
| Sex (male/female) | 6/14 | 11/19 | 0.24 | 1 | 0.626 |
| Age (years) | 33.6 (8.0) | 28.7 (8.6) | F = 8.05 | 1/48 | 0.040 |
| Education (years) | 16.1 (2.2) | 15.6 (1.4) | F = 1.07 | 1/48 | 0.303 |
| Smoking | 18/2 | 23/7 | FEPT | – | 0.285 |
| BMI (kg/m2) | 21.3 (2.5) | 25.5 (5.9) | F = 8.82 | 1/48 | 0.005 |
| HAMD | 1.0 (1.6) | 23.5 (5.8) | F = 281.87 | 1/48 | < 0.001 |
| M1 macrophage (z scores) | −0.131 (0.116) | 0.087 (0.205) | W = 0.86 | 1/48 | 0.354 |
| T helper-1 (z scores) | −0.337 (0.119) | 0.225 (0.198) | W = 5.59 | 1/48 | 0.018 |
| IRS (z scores) | −0.366 (0.114) | 0.244 (0.184) | W = 7.91 | 1/48 | 0.005 |
| T cell growth (z scores) | −0.305 (0.110) | 0.203 (0.169) | W = 6.64 | 1/48 | 0.011 |
| Neurotoxicity (z scores) | −0.286 (0.125) | 0.190 (0.197) | W = 4.09 | 1/48 | 0.043 |
| CD3% | 63.8 (16.7) | 66.1 (10.5) | F = 0.34 | 1/47 | 0.056 |
| CD4% | 53.3 (7.8) | 53.3 (9.2) | F = 0.00 | 1/47 | 0.976 |
| CD8% | 29.8 (8.2) | 32.1 (7.8) | F = 0.91 | 1/47 | 0.344 |
Results are shown as mean (± SD).
FEPT Fisher’s exact probability test, X2 analysis of contingency tables, F results of analysis of variance, W results of general estimating equation (GEE), the p values are results of pairwise comparisons between MDD and controls, BMI body mass index, HAMD Hamilton Depression Rating Scale score, IRS immune-inflammatory responses system.