Table 3.
Differences in unstimulated (UNST) and stimulated (STIM) changes in the percentage of T regulatory (Treg) lymphocyte populations in healthy controls (HC) and major depressed patients (MDD).
| Condition | Diagnosis | Tests of model effects | ||||
|---|---|---|---|---|---|---|
| Variables (z scores) |
HC (n = 20) | MDD (n = 30) | Effects | Wald df = 1 | p | |
| CD25+ FoxP3+ CB1+ % | UNST | −0.238 (0.290) | −0.879 (0.123) | G | 2.66 | 0.103 |
| STIM | 0.599 (0.124) | 0.643 (0.070) | G X T | 4.468 | 0.035 | |
| CD25+ FoxP3+ CD152+ % | UNST | −0.390 (0.222) | −0.873 (0.159) | G | 3.565 | 0.059 |
| STIM | 0.780 (0.095) | 0.619 (0.077) | G X T | 1.659 | 0.198 | |
| CD25+ FoxP3+ GARP+ % | UNST | −0.523 (0.216) | −0.907 (0.138) | G | 1.134 | 0.287 |
| STIM | 0.719 (0.079) | 0.778 (0.064) | G X T | 3.359 | 0.067 | |
Results are shown as estimated marginal mean values (SE).