Successful reconstitution of the donor BMC population in the recipient
(A) Representative overlaid scatterplot of splenocytes from a CD45.1+ donor (blue, AD or WT) and a CD45.2+ recipient mouse (red, APP KO) before bone marrow reconstitution.
(B) Representative scatterplot of PBMCs from a CD45.2+ APP KO mouse, reconstituted with CD45.1+ bone marrow from a donor mouse (AD or WT), 2 months post transplant. The recipient APP KO mouse is 91.5% CD45.1 positive, indicating successful reconstitution.