Figure 5.

Presence of amyloid plaques in AD→WT mice suggests establishment of AD pathology in WT mice through a bone marrow transplant

(A) Micrographs are representative of the cortical region of mouse brains.

(B) Congo red staining indicates the establishment of amyloid plaques in AD→WT mice, which is seen to be significantly higher as compared to WT and similar to the levels seen in AD animals. Each data point in the histograms corresponds to data from individual mice in each group, where n = 6 for WT, n = 8 for AD, and n = 8 for AD→WT. Data is represented as mean ± SD. Ordinary one-way ANOVA was used to calculate significance (p ≤ 0.05).