Table 1. Summary of previously reported cases of primary intracranial ES in patients over 30 years of age (only genetically confirmed cases).
| Study | Age/sex | Symptom duration (mo) | Location | Tumor bed | Diameter (cm) | MRI | Local invasion | Treatment | Recurrence | Follow-up (mo) | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| T1WI | T2WI | ||||||||||
| Batur [17] | 44/M | Headache | Left posterior fossa | Dura | - | High | Iso | N | Gross total removal | N | Alive |
| 4 | 36 | ||||||||||
| Jiang et al. [2] | 55/F | Memory decline | Left frontal lobe | Dura | 6.5 | Low-Iso | Low-High | Bone | Gross total removal | N | Alive |
| 1 | RTx | 18 | |||||||||
| Chen et al. [5] | 43/M | Epilepsy | Right parietal lobe | Dura | - | Low-Iso | Low-High | N | Gross total removal | Y | Dead |
| 1 | CTx (VAC+Actinomycin D) | 48 | |||||||||
| RTx | |||||||||||
| Ke et al. [18] | 43/M | Epilepsy | Right parietal lobe | Dura | - | Low-Iso | Low-High | N | Gross total removal | Y | Dead |
| - | CTx (VACA/VAIA) | 48 | |||||||||
| RTx | |||||||||||
| VandenHeuvel et al. [8] | 61/M | Left hemiparesis | Right frontal lobe | Dura | 6.2 | Low | - | N | Biopsy | - | F/U loss |
| Salunke et al. [9] | 52/M | Headache | Posterior fossa | Dura | 6 | - | - | Bone | Gross total removal | Y | Dead |
| Ataxia | CTx (VACI) | 6.5 | |||||||||
| 1 | RTx | ||||||||||
| Mellai et al. [10] | 56/F | Headache | Right temporal lobe | Dura | - | Low | High | N | Gross total removal | N | Alive |
| Left hemiparesis | 18 | ||||||||||
| - | |||||||||||
| Attabib et al. [11] | 48/F | Headache | Left cavernous sinus | Dura | 4 | - | - | N | Partial removal | N | Alive |
| Left ptosis | CTx (VCD) | 12 | |||||||||
| 6 | RTx | ||||||||||
| D’Antonio et al. [19] | 50/F | Headache | Right parieto-temporal lobe | Dura | 6 | Iso | Low | N | Gross total removal | N | Alive |
| Vomiting | 12 | ||||||||||
| Drowsiness | |||||||||||
| - | |||||||||||
| Hyun et al. [20] | 38/F | Tinnitus | Right petrous ridge | Dura | 6 | - | - | N | Gross total removal | N | Alive |
| Hemiparesis | CTx (VAC/IE) | 12 | |||||||||
ES, Ewing sarcoma; T1WI, T1-weighted image; T2WI, T2-weighted image; RTx, radiotherapy; CTx, chemotherapy; V, vincristine; A, adriamycin; C, cyclophosphamide; I, ifosfamide; D, doxorubicin; E, etoposide