Table 4.
The 20 largest observed global treatment option groups for glycated hemoglobin as the target outcome variable. The list shows the size of each group and the associated percentage controlled during follow-up (n=12,129).
| Treatment option | Frequency, n (%) | DPsa controlled, n (%) |
| No change | 5747 (47.38) | 2541 (44.21) |
| Metformin_new+healthy lifestyle_metformin_stopb | 1324 (10.92) | 605 (45.69) |
| Healthy lifestyle_new+healthy lifestyle_metformin_stopc | 402 (3.31) | 170 (42.29) |
| Metformin_new+no treatment_stopb | 370 (3.05) | 213 (57.57) |
| Healthy lifestyle_metformin_new+metformin_stopb | 324 (2.67) | 210 (64.81) |
| Healthy lifestyle_metformin_new+healthy lifestyle_stopb | 246 (2.03) | 165 (67.07) |
| Healthy lifestyle_metformin_new+no treatment_stopb | 222 (1.83) | 138 (62.16) |
| Gliclazide_healthy lifestyle_new+healthy lifestyle_metformin_STOPc | 217 (1.79) | 86 (39.63) |
| Metformin_new+healthy lifestyle_STOPb | 169 (1.39) | 91 (53.85) |
| Gliclazide_new+healthy lifestyle_metformin_stopc | 151 (1.24) | 65 (43.05) |
| Gliclazide_new+metformin_stopb | 148 (1.22) | 80 (54.05) |
| Gliclazide_metformin_new+gliclazide_healthy lifestyle_metformin_stopc | 147 (1.21) | 38 (25.85) |
| Gliclazide_new+gliclazide_healthy lifestyle_stopc | 123 (1.01) | 41 (33.33) |
| Healthy lifestyle_new+no treatment_stopb | 98 (0.81) | 63 (64.29) |
| Gliclazide_healthy lifestyle_metformin_new+healthy lifestyle_metformin_stopb | 68 (0.56) | 32 (47.06) |
| Gliclazide_metformin_new+metformin_stopc | 59 (0.49) | 30 (50.85) |
| Metformin_new+gliclazide_healthy lifestyle_stopb | 59 (0.49) | 16 (27.12) |
| Gliclazide_healthy lifestyle_new+gliclazide_healthy lifestyle_metformin_stopc | 58 (0.48) | 17 (29.31) |
| Healthy lifestyle_metformin_new+gliclazide_healthy lifestyle_stopc | 58 (0.48) | 12 (20.69) |
| Healthy lifestyle_metformin_new+gliclazide_healthy lifestyle_metformin_stopc | 57 (0.47) | 21 (36.84) |
aDP: decision point.
bTreatment options with a controlled percentage higher than the “no change” treatment option.
cTreatment options with a lower percentage than the “no change” treatment option.