Table 5.
The 20 largest observed global treatment option groups for fasting glucose as the target outcome variable. The list shows the size of each group and the associated percentage controlled during follow-up (n=28,710).
| Treatment option | Frequency, n (%) | DPsa controlled, n (%) |
| No change | 16,480 (57.4) | 3839 (23.29) |
| Metformin_new+healthy lifestyle_metformin_stopb | 3130 (10.9) | 586 (18.72) |
| Healthy lifestyle_new+healthy lifestyle_metformin_stopb | 1011 (3.52) | 201 (19.88) |
| Metformin_new+no treatment_stopb | 639 (2.23) | 110 (17.21) |
| Healthy lifestyle_new+no treatment_stopc | 638 (2.22) | 203 (31.82) |
| Healthy lifestyle_metformin_new+metformin_stopb | 612 (2.13) | 59 (9.64) |
| Healthy lifestyle_metformin_new+healthy lifestyle_stopc | 429 (1.49) | 157 (36.6) |
| Healthy lifestyle_metformin_new+no treatment_stopb | 399 (1.39) | 69 (17.29) |
| Gliclazide_metformin_new+gliclazide_healthy lifestyle_metformin_stopb | 284 (0.99) | 28 (9.86) |
| Metformin_new+healthy lifestyle_stopc | 265 (0.92) | 97 (36.6) |
| Gliclazide_healthy lifestyle_new+healthy lifestyle_metformin_stopb | 259 (0.9) | 32 (12.36) |
| Gliclazide_new+gliclazide_healthy lifestyle_stopb | 223 (0.78) | 39 (17.49) |
| Gliclazide_new+healthy lifestyle_metformin_stopc | 204 (0.71) | 54 (26.47) |
| Gliclazide_new+metformin_stopb | 165 (0.57) | 22 (13.33) |
| Gliclazide_healthy lifestyle_metformin_new+healthy lifestyle_metformin_stopb | 105 (0.37) | 5 (4.76) |
| Healthy lifestyle_new+metformin_stopb | 102 (0.36) | 15 (14.71) |
| Metformin_new+gliclazide_healthy lifestyle_stopb | 102 (0.36) | 13 (12.75) |
| Gliclazide_metformin_new+gliclazide_healthy lifestyle_stopb | 98 (0.34) | 8 (8.16) |
| Healthy lifestyle_metformin_new+gliclazide_healthy lifestyle_stopb | 93 (0.32) | 6 (6.45) |
| Metformin_tolbutamide_new+healthy lifestyle_metformin_tolbutamide_stopb | 91 (0.32) | 2 (2.2) |
aDP: decision point.
bTreatment options with a controlled percentage lower than the “no change” treatment option.
cTreatment options with a controlled percentage higher than the “no change” treatment option.