Figure 1. Cell Plot (Heat Map) of Individual Responses to (A) Nitrous Oxide vs (B) Placebo as Measured on the Hamilton Depression Rating Scale (HDRS) Suicide Item (Item 3)^a.

^aColor indicates severity of suicidal thinking (see figure key). Time points used were prior to inhalation, to establish a baseline, and 2 hours and 24 hours following inhalation. Each row represents a subject. An “x” indicates subjects that had a meaningful reduction in suicidal thinking.