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. 2024 May 3;8:90–198. doi: 10.5414/ALX02444E

Table 8. Differential diagnosis of extrinsic allergic alveolitis (EAA) and organic dust toxic syndrome (ODTS) [354].

Features EAA ODTS
Exposure Various allergens Endotoxins, high exposure
Incidence 2 – 30 / 10,000 10 – 100 / 10,000
Latency 4 – 8 hours 4 – 12 hours
Auscultation End-expiratory rales on both sides basal Normal, possibly rattling noises
Lung function Restriction (rarely obstruction, DLCO reduced Normal (possible restriction)
Precipitins Often specific IgG Mostly negative